Dry skin: how to restore the skin barrier sustainably?

Dry skin affects a large part of the population, particularly in winter or after aggressive dermatological treatments. It is characterized by dehydrated epidermis, feelings of tightness, and even flaking. To restore the skin barrier in a lasting way, it is essential to understand its physiological mechanisms and rely on scientifically validated solutions.

🔬 Understanding the skin barrier

The skin barrier is mainly made up of the stratum corneum, composed of dead keratinocytes and intercellular lipids (ceramides, cholesterol, fatty acids). This structure prevents water loss and protects the skin against external aggressions. When it is altered, there is an increase in transepidermal water loss (TEWL) and increased penetration of external irritants [1] .

💡 Common causes of dry skin

• Exposure to cold, wind, dry air or heating
• Use of detergent soaps, harsh shower gels or chemical exfoliants
• Skin pathologies: eczema, atopic dermatitis, psoriasis [2]
• Drying drugs: retinoids, cancer treatments, etc. [3]
• Age (thinner skin, loss of lipid production over time)

🧴 Recommended active ingredients to repair the skin barrier

Ceramides

Ceramides are lipids naturally present in the stratum corneum. Their topical application helps to restore the lipid barrier and limit transepidermal water loss [4] .

Hyaluronic acid

A powerful humectant, hyaluronic acid attracts and retains up to 1000 times its weight in water. It helps to rehydrate the epidermis in depth [5] .

Vegetable glycerin

It captures ambient humidity and keeps it on the surface of the skin. Tolerated by sensitive skin [6] .

Niacinamide (vitamin B3)

Anti-inflammatory active ingredient that promotes the production of ceramides and strengthens the barrier function [7] .

Butters and vegetable oils

Shea butter, sweet almond oil or avocado oil provide essential fatty acids which replenish the skin's lipids [8] .

✔️ Validated usage instructions

• Apply the moisturizer immediately after showering to skin that is still slightly damp to maximize the occlusive effect [6] .
• Use a soap-free cleanser (syndet) with physiological pH to avoid damaging the hydrolipidic film [2] .
• Avoid water that is too hot, which promotes skin dehydration.
• Apply a cream containing ceramides and niacinamide morning and evening for long-lasting restorative action.

🛍 Products available on Pharmaplusfrance.store

• Ceramide and hyaluronic acid repair cream : restores the skin barrier and deeply rehydrates. Dermatologically tested, fragrance-free and paraben-free.
• Rich treatment with shea butter and niacinamide : soothes, nourishes and protects atopic and very dry skin.
• Gentle cleansing gel with physiological pH : soap-free, sulfate-free, recommended for daily cleansing of dry or irritated skin.

📌 Conclusion

Dry skin isn't inevitable. With a tailored routine based on scientifically proven active ingredients, it's possible to sustainably restore the skin barrier and regain comfort and suppleness. The products offered on Pharmaplusfrance.store incorporate these solutions into tested and effective formulations that are gentle on sensitive skin.

📚 Scientific references

1. ANSM. Skin barrier impairment: mechanisms and treatments. Report, 2022.
2. French National Authority for Health. Atopic dermatitis: Best practice recommendations. HAS, 2020.
3. EMA. Summary of Product Characteristics – Acitretin. European Medicines Agency.
4. Draelos ZD. Ceramide-containing moisturizers: Barrier repair in dermatology. *Am J Clin Dermatol*, 2018.
5. Ganceviciene R. et al. Skin anti-aging strategies. *Dermatoendocrinol*. 2012.
6. Vidal.fr. Vegetable glycerin: topical uses and epidermal hydration.
7. Tanno O. et al. Skin hydration and epidermal barrier function. *Journal of Dermatological Science*, 2000.
8. Fuchs J. et al. Efficacy of natural oils in the treatment of dry skin. *Journal of Cosmetic Dermatology*, 2010.

🛡️ Legal Notices – Comprehensive Disclaimer
This content is published by Groupe Nobélis SASU, a simplified joint-stock company registered with the Paris Trade and Companies Register under number 941 724 544, whose registered office is located at 1 rue de Stockholm, 75008 Paris. The company operates the online parapharmacy website www.pharmaplusfrance.store.
All articles, advice, information, or content published on this blog are provided for purely informative, educational, and non-contractual purposes. They have no medical purpose and should not, under any circumstances, be interpreted as medical advice, consultation, diagnosis, prescription, or treatment recommendation.
In accordance with the provisions of Regulation (EC) No. 1924/2006 on nutrition and health claims, the Public Health Code (in particular articles L.5122-15 et seq.), and the Consumer Code (article L.111-1), we expressly remind you that:

• No information on this site replaces the advice of a qualified health professional,
• Self-medication or the use of products without medical advice is entirely the responsibility of the user,
• Any unauthorized health or nutritional claim is formally excluded from our communications, unless expressly mentioned by a validated regulatory source (EFSA, ANSM, EMA, etc.).

The user agrees to:

• Read the official product instructions carefully before use,
• Strictly follow the dosage, contraindications and precautions for use indicated by the manufacturers,
• Consult a healthcare professional in case of doubt, pathology, ongoing treatment, pregnancy or breastfeeding.

Groupe Nobélis SASU declines all responsibility:

• In case of misinterpretation of the published information,
• In the event of involuntary errors, omissions or inaccuracies despite the care taken in drafting,
• In the event of direct or indirect consequences linked to the use of the products or advice mentioned on this site,
• In the event of changes made to the product instructions or formulas by the manufacturers, after publication.

The site may contain links to products available for sale. The visuals, texts, characteristics and prices are provided for informational purposes only, subject to typographical errors, modifications by brands or regulatory changes. These elements do not constitute a contractual commitment on the part of Groupe Nobélis SASU.
By browsing this site or using its contents, the user acknowledges having read this disclaimer and accepts it without reservation.